�US researchers estimated that the risk of relapse for breast cancer patients who were cancer-free for five years after systemic therapy
(chemotherapy, hormone therapy, or both, as well as operating room) was not negligible although it was probably lower than many people realized.
The study was the ferment of Dr Abenaa Brewster of the University of Texas MD Anderson Cancer Center in Houston and colleagues and is promulgated
in the August 11 online issue of the Journal of the National Cancer Institute.
Brewster and colleagues wrote that women wHO receive adjuvant or systemic therapy (that is chemotherapy or endocrine treatment, or both) as well as
surgery throw a higher survival pace free of cancer than women world Health Organization do not have this type of treatment, only few studies have examined this put up
treatment period, the size of the recurrence risk, and the types of tumors that can occur.
When they explored this region, they found that for breast cancer patients wHO were cancer-free five years after the start of systemic therapy, 89 per
cent of them survived another v years, and 80 per cent of them survived another 10 years, which was about 15 old age after receiving their initial
diagnosis and starting treatment.
For the study, Brewster and colleagues examined records of 2,838 breast cancer patients wHO were on the MD Anderson Cancer Center's neoplasm
registry and were treated between 1985 and 2001. They looked at what happened pentad years after the women started treatment so they could work
out the risk of relapse afterwards adjuvant therapy, which might include five-spot years of hormone therapy.
The study mostly predates the introduction around the year 2000 of a newer class of hormone targeting drugs, the aromatase inhibitors, which is now
often used to treat hormone-sensitive tumors instead of the more traditional tamoxifen. The number of women in the study who were treated with the
newer drugs was very small and the relevance of these findings for them is non clear, the researchers told WebMD.
Nevertheless, for the women in the study, the authors plant that:
216 women developed recurrent disease after a median followup of 28 months.
For women with stage I breast cancer, the five year risk of relapse was 7 per cent.
This was 11 per cent for women with stage II cancer, and 13 per cent for women with stage III.
Risk of recurrence was significantly linked to tumor level, whether the cancer was hormone-sensitive, and whether hormone therapy was
administered.
Brewster and colleagues ended that:
"This study demonstrates that patients with early stage breast cancer the Crab who are disease give up at basketball team years afterwards [adjuvant systemic therapy] accept a
substantially increased residual risk of recurrence."
The authors wrote that the increased risk of relapse after five days of therapy for patients with hormone-sensitive cancer "points to an area of unmet
clinical need", because while options to thin out risk exist for postmenopausal women later on five age on estrogen antagonist, there ar none for premenopausal
women and new strategies ar needed to help these patients lose weight their relapse risk.
The authors also told WebMD that the study revealed good news for women world Health Organization have chest cancers that are estrogen-receptor negative (ER
negative), that is their tumors do not trust on oestrogen to grow. Although less common, these cancers ar usually considered more deadly than the
hormone sensitive type.
The study showed that patients with ER negative tumors wHO survived for five years after starting treatment had a better prognosis than patients with
ER positive tumors, as Brewster told WebMD:
"These tumors are certainly more fast-growing early on, but the outlook is good for women with these tumors who make it for five-spot years," adding that, "
we can now tell these women that their risk for developing a return is lour than for women with ER-positive tumors."
"Breast Cancer Patients Still Have Risk of Relapse After Five Years of Systemic Therapy."
Journal of the National Cancer Institute Advance Access published on August 11, 2008.
doi:10.1093/jnci/djn323
Click here for Abstract.
Sources: JNCI, WebMD.
Written by: Catharine Paddock, PhD
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today
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Saturday, 6 September 2008
Wednesday, 27 August 2008
Download Danger Man mp3
Artist: Danger Man: mp3 download Genre(s): Other Discography: Fenomeno Year: 2004 Tracks: 26 The New York City-based altitude belt down span Dangerman comprised singer/guitarist Chris Scianni and drummer Dave Borla, longtime veterans of the local music scene humanity Health Organization began collaborating in 1997. After touring with acts of the Apostles of the Apostles ranging from Luscious Jackson to Fun Lovin' Criminals, Dangerman recruited producer Brendan O'Brien to begin work on their self-titled debut LP, issued on Sony's 550 imprint in 1999. |
Sunday, 17 August 2008
Influential Brazilian singer-songwriter Caymmi dies
SAO PAULO () - Brazilian singer-songwriter Dorival Caymmi, who
Thursday, 7 August 2008
Monday, 30 June 2008
Lights For Nero
Artist: Lights For Nero
Genre(s):
Other
Discography:
And Little Lambs Eat Nation
Year: 2004
Tracks: 10
 
Pedro Fernandez
Wednesday, 25 June 2008
Shirley Bassey to miss Mandela concert in London
LONDON (Reuters) - Welsh-born singer Shirley Bassey has pulled out of Friday's London concert to celebrate former South African President Nelson Mandela's 90th birthday.
The 71-year-old, best known for her James Bond movie theme songs "Goldfinger" and "Diamonds Are Forever," underwent emergency surgery on her stomach in May and was advised by doctors not to travel to London from her home in Monaco.
"On the advice of her surgeon, Dame Shirley Bassey will now not be able to perform as scheduled at the Nelson Mandela 46664 concert," said her spokesman.
"The dame is hugely disappointed and was looking forward to the show immensely. Dame Shirley has been advised not to travel at the present time, so as to aid her continued full recovery following surgery last month."
The concert, in London's Hyde Park, is expected to feature acts including Queen, Leona Lewis, Annie Lennox, Simple Minds and Razorlight.
Proceeds from the concert will go to the 46664 global campaign against HIV/AIDS, named after Mandela's prison number.
Reuters/Nielsen
The 71-year-old, best known for her James Bond movie theme songs "Goldfinger" and "Diamonds Are Forever," underwent emergency surgery on her stomach in May and was advised by doctors not to travel to London from her home in Monaco.
"On the advice of her surgeon, Dame Shirley Bassey will now not be able to perform as scheduled at the Nelson Mandela 46664 concert," said her spokesman.
"The dame is hugely disappointed and was looking forward to the show immensely. Dame Shirley has been advised not to travel at the present time, so as to aid her continued full recovery following surgery last month."
The concert, in London's Hyde Park, is expected to feature acts including Queen, Leona Lewis, Annie Lennox, Simple Minds and Razorlight.
Proceeds from the concert will go to the 46664 global campaign against HIV/AIDS, named after Mandela's prison number.
Reuters/Nielsen
Wednesday, 18 June 2008
Planet Patrol
Artist: Planet Patrol
Genre(s):
Electronic
Discography:
Planet Patrol
Year: 1982
Tracks: 9
Produced and unionised by early hip-hop impresarios Arthur Baker and John Robie, Planet Patrol walked an intriguing note between electro and the classic Motown sound. The fivesome of vocalists (light-emitting diode by Herb Jackson) only produced one and only album, simply it is one and only of the few hellenic LPs of the electro eRA.
Saturday, 14 June 2008
Juliana Hatfield
Artist: Juliana Hatfield
Genre(s):
Rock
Other
Discography:
Made in China
Year: 2005
Tracks: 12
In Exile Deo
Year: 2004
Tracks: 13
Juliana's Pony: Total System Failure
Year: 2000
Tracks: 13
God's Foot
Year: 2000
Tracks: 16
Beautiful Creature
Year: 2000
Tracks: 13
Bed
Year: 1998
Tracks: 10
Please Do Not Disturb
Year: 1997
Tracks: 6
Only Everything
Year: 1995
Tracks: 17
I See You
Year: 1992
Tracks: 5
Hey Babe
Year: 1992
Tracks: 11
Bowery Ballroom
Year:
Tracks: 10
After Juliana Hatfield disbanded the jangle pop trinity the Blake Babies in 1990, she launched a solo life history, performing similarly melodic indie guitar pop. Singing in an endearingly tenuous voice, Hatfield married her ring hooks to gratifying, bereft pop and startlingly good confessional songs. Her 1992 solo debut, Hey Babe, became a college radio hit, and its follow-up, 1994's Become What You Are, was primed to suit a crossover success in the wake of the commercialization of alternate rock-and-roll. Although Hatfield had a smattering of modern tilt hits, including "Spin the Bottle," she ne'er managed to hit the mainstream audience of peers wish the Lemonheads did, and by the late '90s, she had settled into a cult following.
Hatfield was brocaded in an upper-middle-class home in Massachusetts; her father was a dr. and her mother was a manner editor program for The Boston Globe. As a baby, she learned how to play piano, and during high school day, she played guitar in a covers grouping called the Squids before discovering alternate tilt through the Velvet Underground. Following high schoolhouse, she tended to the Berklee College of Music in Boston, where she studied voice. While at Berklee, she met guitar player John Strohm and drummer Freda Boner, with whom she formed the Blake Babies in 1986. Over the next six years, the Blake Babies and their charming jangle pop became college radio receiver favorites. Hatfield leftfield the band in 1990, and Strohm and Boner formed Antenna.
Immediately following her leaving from the Blake Babies, Hatfield contributed several lyrics to Susanna Hoffs' debut album. The following year, she played bass on the Lemonheads' It's a Shame About Ray, which turned out to be the band's commercial breakthrough. The success of It's a Shame About Ray in 1992 stirred interest in Hatfield's solo debut, Hey Babe. Released on Mammoth Records, the record album was identical interchangeable to the Blake Babies, yet the songs were more personal and confessional. Hey Babe was critically praised and became a college radio and MTV hit, ahead to a major-label contract for Hatfield with Atlantic.
In 1992, Hatfield formed the Juliana Hatfield Three with bassist Dean Fisher and drummer Todd Phillips, and the mathematical group recorded its debut for Atlantic with R.E.M.'s producer, Scott Litt. As she worked on the record, Hatfield became a venial media sense experience; her songs were accepted as friendly, more accessible distillations of the women's liberationist alternative rock movement known as riot grrrl. Hatfield appeared in fashion layouts in Vogue and Sassy, and she became the subject of chatty tidbits well-nigh her speculated romance with Lemonhead Evan Dando and her averment that she was still a virgin at the old age of 25. In light of such exposure, many observers expected her 1993 album Become What You Are to be her mainstream discovery. A heavier record than its herald, Turn What You Are was a curb hit, as "My Sister" and "Spin the Bottle" earned heavy airplay on MTV and modern rock wireless. Nevertheless, the album failed to make her a star.
Only Everything followed in the spring of 1995 as alternative rock was origin to decline in popularity. The album was received with motley reviews, and only "Universal joint Heartbeat" managed to make much clearance on receiving set or MTV, causing the album to sideslip down pat the charts cursorily. Hatfield returned in 1997 with the EP Please Do Not Disturb, followed a year by and by by the full-length Bed. Spring 2000 was a busy time for Hatfield; she released the hushed, reflective solo record album Beautiful Creature and Total System Failure, a collection of louder, poppier material, on the same day. Total System Failure featured Hatfield, quondam Weezer bassist Mike Welsh, and drummer Zephan Courtney as a new banding, Juliana's Pony, which was a iII along the lines of the Juliana Hatfield Three.
Hatfield's following project was a devolve to one of her first gear: in 2000 she reunited with Freda Love and John Strohm, launching a Blake Babies tour and recording an record album, Supreme Being Bless the Blake Babies. The reunion was transitory, only Hatfield and Love continued to work together in a radical called Some Girls, which besides featured Heidi Gluck (the Pieces). Some Girls place extinct the Feel It LP in 2002 and besides did some touring. After that it was back to the solo game for Hatfield. But 2004's In Exile Deo was a bit of a surprise, since later on all her restlessness it was easily one of her strongest, most grow albums. That ripen streak continued with 2005's Made in China, a rude and direct endeavour that she produced herself and put extinct through her possess Ye Olde imprint, and deuce eld later the EP Sittin' in a Tree... with mate Bostonians Frank Smith, an alt-country set, was released, as well as a assemblage of live recordings called The White Broken Line: Live Recordings.
Natasha Bedingfield joins New Kids
Will be opening act for reunion tour
NEW YORK -- Natasha Bedingfield has been drafted as the opening act for most of New Kids on the Block's upcoming reunion tour. The trek begins Sept. 18-19 in Toronto and runs through Nov. 26 in Los Angeles.
Bedingfield is enjoying a top 10 Hot 100 hit with "Pocketful of Sunshine," also the title track of her latest Epic album. The song is No. 9 in its 17th week, while the album is No. 45 on The Billboard 200 in its 20th. It has sold 275,000 copies in the U.S., according to Nielsen SoundScan.
The artist is currently on the Verizon VIP Tour, performing with Kate Voegele and the Veronicas, through July 10 in San Francisco.
NEW YORK -- Natasha Bedingfield has been drafted as the opening act for most of New Kids on the Block's upcoming reunion tour. The trek begins Sept. 18-19 in Toronto and runs through Nov. 26 in Los Angeles.
Bedingfield is enjoying a top 10 Hot 100 hit with "Pocketful of Sunshine," also the title track of her latest Epic album. The song is No. 9 in its 17th week, while the album is No. 45 on The Billboard 200 in its 20th. It has sold 275,000 copies in the U.S., according to Nielsen SoundScan.
The artist is currently on the Verizon VIP Tour, performing with Kate Voegele and the Veronicas, through July 10 in San Francisco.
Woody Allen fears for Scarlett Johansson
Veteran film director Woody Allen is fearful that Scarlett Johansson will ruin her promising acting career by indulging in the party lifestyle.
The director, who has worked with Johansson on a number of movies, has said she is one of the most talented stars of her generation and has advised her to follow Meryl Streep's example.
He told the New York Post's gossip column Page Six: "(Johansson) is so beautiful and so sexy and so gifted... she can do anything, but she has to make the right choices of films and she's got to not go the Page Six party route.
"I don't want to read about her in the paper with this boyfriend or that boyfriend, or in rehab or taking pills. I don't think she's always made great choices. She has to take her acting seriously... the way someone like Meryl Streep did it."
The director, who has worked with Johansson on a number of movies, has said she is one of the most talented stars of her generation and has advised her to follow Meryl Streep's example.
He told the New York Post's gossip column Page Six: "(Johansson) is so beautiful and so sexy and so gifted... she can do anything, but she has to make the right choices of films and she's got to not go the Page Six party route.
"I don't want to read about her in the paper with this boyfriend or that boyfriend, or in rehab or taking pills. I don't think she's always made great choices. She has to take her acting seriously... the way someone like Meryl Streep did it."
Break
Artist: Break
Genre(s):
Drum & Bass
Rock
Other
Discography:
The Myth
Year: 2006
Tracks: 2
Subtitles (SUBTITLES043)
Year: 2005
Tracks: 2
Subtitles (SUBTITLES039)
Year: 2005
Tracks: 2
Submerged / Today's Special
Year: 2005
Tracks: 2
Invaderz Transmissions (INV009)
Year: 2005
Tracks: 2
Diffusion / Locked Out
Year: 2005
Tracks: 2
Commercial Suicide (SUICIDE030)
Year: 2005
Tracks: 2
Positive-Negative Hearing Voices
Year: 2004
Tracks: 1
Handbook For The Hopeless
Year: 2004
Tracks: 11
 
Jack Black - Fascinating Fact 5417
It pays to know funnyman JACK BLACK - pal and TENACIOUS D bandmate KYLE GASS and his wife TANYA HADEN both have speaking parts in his new animated film KUNG FU PANDA.
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Kielty facing speeding charge
Northern Irish star Patrick Kielty is set to face a speeding charge in court next month, according to reports.
The Co Down comedian and TV presenter is accused of driving at 101mph in Scotland in December of last year.
37-year-old Kielty was stopped by police on the A75 Gretna to Stranraer road in Dumfries and Galloway.
The case was due to be heard today but has been put back to 22 April, at which date Kielty is expected to make a plea.
The Co Down comedian and TV presenter is accused of driving at 101mph in Scotland in December of last year.
37-year-old Kielty was stopped by police on the A75 Gretna to Stranraer road in Dumfries and Galloway.
The case was due to be heard today but has been put back to 22 April, at which date Kielty is expected to make a plea.
Pink Twins
Artist: Pink Twins
Genre(s):
Industrial
Discography:
Motor Sessions
Year: 2001
Tracks: 3
Weight Without Motion
Year: 2000
Tracks: 2
Punk Twins
Year: 2000
Tracks: 8
Wu
Year: 1999
Tracks: 18
Pink Boys
Year: 1999
Tracks: 7
Passive Guidance
Year: 1999
Tracks: 6
Concerto Grosso
Year: 1999
Tracks: 1
Latent Heat of Vapourization
Year: 1998
Tracks: 3
 
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